Tag: opioid constipation

Managing Opioid Constipation with Peripherally Acting Mu Antagonists
Managing Opioid Constipation with Peripherally Acting Mu Antagonists
Graham Everly January 30, 2026

PAMORAs are the only drugs that treat opioid-induced constipation without reducing pain relief. Learn how methylnaltrexone, naloxegol, and naldemedine work, their effectiveness, side effects, and real-world costs.