Tag: fibromyalgia pain
Fibromyalgia Pain: How Antidepressants Help Manage Widespread Chronic Pain
Graham Everly
February 3, 2026
Fibromyalgia causes widespread, chronic pain that doesn't respond to typical treatments. Antidepressants like amitriptyline and duloxetine help by calming overactive pain signals in the nervous system - not by treating depression. Learn how they work, what to expect, and why they're a key part of managing this condition.